You can try, Wednesday, but you'll never make me as worn out as I made your mom. (NSFW language)

If the week was an audience, Wednesday would be the guy who got too drunk with his college buddies and forgot that he's not funny outside of his hometown bar. Wednesday is the obnoxious bachelorette party (bear with me on this metaphor, here) that makes everyone else want to leave by screaming and waving foam penises in the air. Wednesday sucks, is what I'm trying to say.

Related: "Famous Comedians Dealing With Hecklers" will help you cope with the idiots in your life.